Anticancer Effect of Pomegranate Peel Polyphenols against Cervical Cancer

Anticancer Effect of Pomegranate Peel Polyphenols against Cervical Cancer

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Polyphenols are a broad group of bioactive phytochemicals with powerful antioxidant, anti-inflammatory, immunomodulatory, and antiviral activities.Numerous studies have demonstrated that polyphenol glitter smoothing top coat extracts obtained from natural sources can be used for the prevention and treatment of cancer.Pomegranate peel extract is an excellent source of polyphenols, such as punicalagin, punicalin, ellagic acid, and caffeic acid, among others.These phenolic compounds have antineoplastic activity in in vitro models of cervical cancer through the regulation of cellular redox balance, induction of apoptosis, cell cycle arrest, and modulation of different signaling pathways.

The current review summarizes recent data from scientific reports that address the anticancer activity of the predominant polyphenol compounds present in PPE and their different mechanisms of action in san diego padres 1998 world series hat cervical cancer models.